Guelph Boy S Journey With Childhood Alzheimer S
A rare and terminal metabolic disorder likened to childhood Alzheimer’s disease, Sanfilippo syndrome affects only about one in 70,000 live births. Among them is eight-year-old Joseph Saliba of Guelph. The condition is characterized by severe symptoms such as progressive dementia, mental retardation, developmental delays, decreased motor skills, aggressive behavior, hyperactivity, some deafness and vision loss, and inability to sleep for more than a few hours at a time. Like many children with Sanfilippo, Joseph appeared healthy at birth and was not diagnosed until he was four....